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Opposing Patterns of Signaling Activation in Dopamine D(1) and D(2) Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol
Psychostimulants and other drugs of abuse activate extracellular signal-regulated kinase (ERK) in the striatum, through combined stimulation of dopamine D(1) receptors (D1Rs) and glutamate NMDA receptors. Antipsychotic drugs activate similar signaling proteins in the striatum by blocking dopamine D(...
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| Publicado no: | J Neurosci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6670792/ https://ncbi.nlm.nih.gov/pubmed/18509028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1039-08.2008 |
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