The Crucial Role of Chromogranins in Storage and Exocytosis Revealed Using Chromaffin Cells from Chromogranin A Null Mouse

Chromogranins (Cgs) are the major soluble proteins of dense-core secretory vesicles. Chromaffin cells from Chga null mice [chromogranin A knock-out (CgA-KO)] exhibited ∼30% reduction in the content and in the release of catecholamines compared with wild type. This was because of a lower secretion pe...

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Publié dans:J Neurosci
Auteurs principaux: Montesinos, Monica S., Machado, J. David, Camacho, Marcial, Diaz, Jesica, Morales, Yezer G., Alvarez de la Rosa, Diego, Carmona, Emilia, Castañeyra, Agustin, Viveros, O. Humberto, O'Connor, Daniel T., Mahata, Sushil K., Borges, Ricardo
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2008
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670582/
https://ncbi.nlm.nih.gov/pubmed/18367602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5292-07.2008
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