Chromogranin B Gene Ablation Reduces the Catecholamine Cargo and Decelerates Exocytosis in Chromaffin Secretory Vesicles

Chromogranins/secretogranins (Cgs) are the major soluble proteins of large dense-core secretory vesicles (LDCVs). We have recently reported that the absence of chromogranin A (CgA) caused important changes in the accumulation and in the exocytosis of catecholamines (CAs) using a CgA-knock-out (CgA-K...

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Pubblicato in:J Neurosci
Autori principali: Díaz-Vera, Jésica, Morales, Yézer G., Hernández-Fernaud, Juan R., Camacho, Marcial, Montesinos, Mónica S., Calegari, Federico, Huttner, Wieland B., Borges, Ricardo, Machado, José D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633114/
https://ncbi.nlm.nih.gov/pubmed/20089903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2894-09.2010
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