Retinal Ganglion Cells Downregulate Gene Expression and Lose Their Axons within the Optic Nerve Head in a Mouse Glaucoma Model

Little is known about molecular changes occurring within retinal ganglion cells (RGCs) before their death in glaucoma. Taking advantage of the fact that γ-synuclein (Sncg) mRNA is expressed specifically and highly in adult mouse RGCs, we show in the DBA/2J mouse model of glaucoma that there is not o...

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Publicado en:J Neurosci
Main Authors: Soto, Ileana, Oglesby, Ericka, Buckingham, Brian P., Son, Janice L., Roberson, Elisha D. O., Steele, Michael R., Inman, Denise M., Vetter, Monica L., Horner, Philip J., Marsh-Armstrong, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2008
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670511/
https://ncbi.nlm.nih.gov/pubmed/18184797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3714-07.2008
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