Retinal Ganglion Cell Loss in a Rat Ocular Hypertension Model Is Sectorial and Involves Early Optic Nerve Axon Loss

PURPOSE. Previous analyses of the DBA/2J mouse glaucoma model show a sectorial degeneration pattern suggestive of an optic nerve head insult. In addition, there are large numbers of retinal ganglion cells (RGCs) that cannot be retrogradely labeled but maintain RGC gene expression, and many of these...

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Main Authors: Soto, Ileana, Pease, Mary E., Son, Janice L., Shi, Xiaohai, Quigley, Harry A., Marsh-Armstrong, Nicholas
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053289/
https://ncbi.nlm.nih.gov/pubmed/20811062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5856
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