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HDAC7‐mediated control of tumour microenvironment maintains proliferative and stemness competence of human mammary epithelial cells

HDAC7 is a pleiotropic transcriptional coregulator that controls different cellular fates. Here, we demonstrate that in human mammary epithelial cells, HDAC7 sustains cell proliferation and favours a population of stem‐like cells, by maintaining a proficient microenvironment. In particular, HDAC7 re...

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Bibliografiske detaljer
Udgivet i:Mol Oncol
Main Authors: Cutano, Valentina, Di Giorgio, Eros, Minisini, Martina, Picco, Raffaella, Dalla, Emiliano, Brancolini, Claudio
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670296/
https://ncbi.nlm.nih.gov/pubmed/31081251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12503
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