HDAC3-Mediated Repression of the Nr4a Family Contributes to Age-Related Impairments in Long-Term Memory

Aging is accompanied by cognitive deficits, including impairments in long-term memory formation. Understanding the molecular mechanisms that support preserved cognitive function in aged animals is a critical step toward identifying novel therapeutic targets that could improve memory in aging individ...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Kwapis, Janine L., Alaghband, Yasaman, López, Alberto J., Long, Jeffrey M., Li, Xiang, Shu, Guanhua, Bodinayake, Kasuni K., Matheos, Dina P., Rapp, Peter R., Wood, Marcelo A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2019
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670247/
https://ncbi.nlm.nih.gov/pubmed/31000586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2799-18.2019
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