DIVERSet JAG Compounds Inhibit Topoisomerase II and Are Effective Against Adult and Pediatric High-Grade Gliomas

High-grade gliomas (HGGs) are aggressive primary brain tumors with local invasive growth and poor clinical prognosis in both adult and pediatric patients. Clinical response is compounded by resistance to standard frontline antineoplastic agents, an absence of novel therapeutics, and poor in vitro mo...

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Detaylı Bibliyografya
Yayımlandı:Transl Oncol
Asıl Yazarlar: Howarth, Alison, Simms, Claire, Kerai, Nitesh, Allen, Olivia, Mihajluk, Karina, Madureira, Patricia A., Sokratous, Giannis, Cragg, Simon, Lee, Sang Y., Morley, Andy D., Ashkan, Keyoumars, Cox, Paul A., Pilkington, Geoffrey J., Hill, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press 2019
Konular:
Original article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669375/
https://ncbi.nlm.nih.gov/pubmed/31374406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.07.007
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