DNMT3A mutation is associated with increased age and adverse outcome in adult T-cell acute lymphoblastic leukemia

The prognostic implications of DNMT3A genotype in T-cell acute lymphoblastic leukemia are incompletely understood. We performed comprehensive genetic and clinico-biological analyses of T-cell acute lymphoblastic leukemia patients with DNMT3A mutations treated during the GRAALL-2003 and -2005 studies...

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Publié dans:Haematologica
Auteurs principaux: Bond, Jonathan, Touzart, Aurore, Leprêtre, Stéphane, Graux, Carlos, Bargetzi, Mario, Lhermitte, Ludovic, Hypolite, Guillaume, Leguay, Thibaut, Hicheri, Yosr, Guillerm, Gaëlle, Bilger, Karin, Lhéritier, Véronique, Hunault, Mathilde, Huguet, Françoise, Chalandon, Yves, Ifrah, Norbert, Macintyre, Elizabeth, Dombret, Hervé, Asnafi, Vahid, Boissel, Nicolas
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669163/
https://ncbi.nlm.nih.gov/pubmed/30655366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.197848
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