An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study

Gene expression studies have consistently identified a HOXA-overexpressing cluster of T-cell acute lymphoblastic leukemias, but it is unclear whether these constitute a homogeneous clinical entity, and the biological consequences of HOXA overexpression have not been systematically examined. We chara...

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Détails bibliographiques
Publié dans:Haematologica
Auteurs principaux: Bond, Jonathan, Marchand, Tony, Touzart, Aurore, Cieslak, Agata, Trinquand, Amélie, Sutton, Laurent, Radford-Weiss, Isabelle, Lhermitte, Ludovic, Spicuglia, Salvatore, Dombret, Hervé, Macintyre, Elizabeth, Ifrah, Norbert, Hamel, Jean-François, Asnafi, Vahid
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013941/
https://ncbi.nlm.nih.gov/pubmed/26944475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.141218
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