Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia

Cancer cells undergo massive alterations in their DNA methylation patterns which result in aberrant gene expression and malignant phenotypes. Abnormal DNA methylation is a prognostic marker in several malignancies, but its potential prognostic significance in adult T-cell acute lymphoblastic leukemi...

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Bibliografiska uppgifter
I publikationen:Haematologica
Huvudupphovsmän: Touzart, Aurore, Boissel, Nicolas, Belhocine, Mohamed, Smith, Charlotte, Graux, Carlos, Latiri, Mehdi, Lhermitte, Ludovic, Mathieu, Eve-Lyne, Huguet, Françoise, Lamant, Laurence, Ferrier, Pierre, Ifrah, Norbert, Macintyre, Elizabeth, Dombret, Hervé, Asnafi, Vahid, Spicuglia, Salvatore
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ferrata Storti Foundation 2020
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7271605/
https://ncbi.nlm.nih.gov/pubmed/31537687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.223677
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