Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice

Platelets promote wound healing by forming a vascular plug and by secreting growth factors and cytokines. Glycoprotein (GP)VI and C-type lectin-like receptor (CLEC)-2 signal through a (hem)-immunoreceptor tyrosine-based activation motif, which induces platelet activation. GPVI and CLEC-2 support vas...

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Publicado no:Haematologica
Main Authors: Wichaiyo, Surasak, Lax, Sian, Montague, Samantha J., Li, Zhi, Grygielska, Beata, Pike, Jeremy A., Haining, Elizabeth J., Brill, Alexander, Watson, Steve P., Rayes, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669159/
https://ncbi.nlm.nih.gov/pubmed/30733265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.208363
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