Differential effects of reduced glycoprotein VI levels on activation of murine platelets by glycoprotein VI ligands.

We have investigated the effects of decreased levels of the complex between glycoprotein VI (GPVI) and the Fc receptor gamma-chain (FcRgamma) on responses to collagen and GPVI-specific ligands in murine platelets. We show that levels of GPVI-FcRgamma of the order of 50% and 20% of wild-type levels c...

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Detalhes bibliográficos
Main Authors: Snell, Daniel C, Schulte, Valerie, Jarvis, Gavin E, Arase, Kanako, Sakurai, Daiju, Saito, Takashi, Watson, Steve P, Nieswandt, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222953/
https://ncbi.nlm.nih.gov/pubmed/12117414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020335
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