Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans

BACKGROUND: Microbial metabolism of lignans from high-fiber plant foods produces bioactive enterolignans, such as enterolactone (ENL) and enterodiol (END). Enterolignan exposure influences cellular pathways important to cancer risk and is associated with reduced colon tumorigenesis in animal models...

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Dettagli Bibliografici
Pubblicato in:Am J Clin Nutr
Autori principali: Lampe, Johanna W, Kim, Eunji, Levy, Lisa, Davidson, Laurie A, Goldsby, Jennifer S, Miles, Fayth L, Navarro, Sandi L, Randolph, Timothy W, Zhao, Ni, Ivanov, Ivan, Kaz, Andrew M, Damman, Christopher, Hockenbery, David M, Hullar, Meredith A J, Chapkin, Robert S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Original Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669062/
https://ncbi.nlm.nih.gov/pubmed/31175806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajcn/nqy325
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