Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans

BACKGROUND: Microbial metabolism of lignans from high-fiber plant foods produces bioactive enterolignans, such as enterolactone (ENL) and enterodiol (END). Enterolignan exposure influences cellular pathways important to cancer risk and is associated with reduced colon tumorigenesis in animal models...

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Detalhes bibliográficos
Publicado no:Am J Clin Nutr
Main Authors: Lampe, Johanna W, Kim, Eunji, Levy, Lisa, Davidson, Laurie A, Goldsby, Jennifer S, Miles, Fayth L, Navarro, Sandi L, Randolph, Timothy W, Zhao, Ni, Ivanov, Ivan, Kaz, Andrew M, Damman, Christopher, Hockenbery, David M, Hullar, Meredith A J, Chapkin, Robert S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669062/
https://ncbi.nlm.nih.gov/pubmed/31175806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajcn/nqy325
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