Colonic mucosal and exfoliome transcriptomic profiling and fecal microbiome response to a flaxseed lignan extract intervention in humans

BACKGROUND: Microbial metabolism of lignans from high-fiber plant foods produces bioactive enterolignans, such as enterolactone (ENL) and enterodiol (END). Enterolignan exposure influences cellular pathways important to cancer risk and is associated with reduced colon tumorigenesis in animal models...

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Dades bibliogràfiques
Publicat a:Am J Clin Nutr
Autors principals: Lampe, Johanna W, Kim, Eunji, Levy, Lisa, Davidson, Laurie A, Goldsby, Jennifer S, Miles, Fayth L, Navarro, Sandi L, Randolph, Timothy W, Zhao, Ni, Ivanov, Ivan, Kaz, Andrew M, Damman, Christopher, Hockenbery, David M, Hullar, Meredith A J, Chapkin, Robert S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Original Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669062/
https://ncbi.nlm.nih.gov/pubmed/31175806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajcn/nqy325
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