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Recombinant vector vaccine evolution
Replicating recombinant vector vaccines consist of a fully competent viral vector backbone engineered to express an antigen from a foreign transgene. From the perspective of viral replication, the transgene is not only dispensable but may even be detrimental. Thus vaccine revertants that delete or i...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6668849/ https://ncbi.nlm.nih.gov/pubmed/31323032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006857 |
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