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Directed attenuation to enhance vaccine immunity

Many viral infections can be prevented by immunizing with live, attenuated vaccines. Early methods of attenuation were hit-and-miss, now much improved by genetic engineering. However, even current methods operate on the principle of genetic harm, reducing the virus’s ability to grow. Reduced viral g...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Antia, Rustom, Ahmed, Hasan, Bull, James J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877766/
https://ncbi.nlm.nih.gov/pubmed/33524036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008602
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