The antibiotic clofoctol suppresses glioma stem cell proliferation by activating KLF13

Gliomas account for approximately 80% of primary malignant tumors in the central nervous system. Despite aggressive therapy, the prognosis of patients remains extremely poor. Glioma stem cells (GSCs), considered a potential target of therapy for their crucial role in therapeutic resistance and tumor...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Hu, Yan, Zhang, Meilian, Tian, Ningyu, Li, Dengke, Wu, Fan, Hu, Peishan, Wang, Zhixing, Wang, Liping, Hao, Wei, Kang, Jingting, Yin, Bin, Zheng, Zhi, Jiang, Tao, Yuan, Jiangang, Qiang, Boqin, Han, Wei, Peng, Xiaozhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668693/
https://ncbi.nlm.nih.gov/pubmed/31112526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI124979
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