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RhoGDIα suppresses self-renewal and tumorigenesis of glioma stem cells

Glioma stem cells (GSCs) are a subset of tumor cells that drive glioma initiation and progression. The molecular mechanisms underlying the maintenance of GSCs are still poorly understood. Here we investigated the role of Rho GDP dissociation inhibitor α (RhoGDIα) in GSCs. RhoGDIα was down-regulated...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wu, Fan, Hu, Peishan, Li, Dengke, Hu, Yan, Qi, Yingjiao, Yin, Bin, Jiang, Tao, Yuan, Jiangang, Han, Wei, Peng, Xiaozhong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308677/
https://ncbi.nlm.nih.gov/pubmed/27557508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11423
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