T follicular helper cells in human efferent lymph retain lymphoid characteristics

T follicular helper cells (Tfh), a subset of CD4(+) T cells, provide requisite help to B cells in the germinal centers (GC) of lymphoid tissue. GC Tfh are identified by high expression of the chemokine receptor CXCR5 and the inhibitory molecule PD-1. Although more accessible, blood contains lower fr...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Vella, Laura A., Buggert, Marcus, Manne, Sasikanth, Herati, Ramin S., Sayin, Ismail, Kuri-Cervantes, Leticia, Bukh Brody, Irene, O’Boyle, Kaitlin C., Kaprielian, Hagop, Giles, Josephine R., Nguyen, Son, Muselman, Alexander, Antel, Jack P., Bar-Or, Amit, Johnson, Matthew E., Canaday, David H., Naji, Ali, Ganusov, Vitaly V., Laufer, Terri M., Wells, Andrew D., Dori, Yoav, Itkin, Maxim G., Betts, Michael R., Wherry, E. John
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668682/
https://ncbi.nlm.nih.gov/pubmed/31264971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125628
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