Spatial distribution and function of T follicular regulatory cells in human lymph nodes

T follicular regulatory (Tfr) cells are a population of CD4(+) T cells that express regulatory T cell markers and have been shown to suppress humoral immunity. However, the precise mechanisms and location of Tfr-mediated suppression in the lymph node (LN) microenvironment are unknown. Using highly m...

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Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Sayin, Ismail, Radtke, Andrea J., Vella, Laura A., Jin, Wenjie, Wherry, E. John, Buggert, Marcus, Betts, Michael R., Herati, Ramin S., Germain, Ronald N., Canaday, David H.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2018
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987920/
https://ncbi.nlm.nih.gov/pubmed/29769249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20171940
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