Inflammasome activation is required for human rhinovirus-induced airway inflammation in naïve and allergen-sensitized mice

Activation of the inflammasome is a key function of the innate immune response which regulates inflammation in response to microbial substances. Inflammasome activation by human rhinovirus (RV), a major cause of asthma exacerbations, has not been well-studied. We examined whether RV induces inflamma...

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Udgivet i:Mucosal Immunol
Main Authors: Han, Mingyuan, Bentley, J. Kelley, Rajput, Charu, Lei, Jing, Ishikawa, Tomoko, Jarman, Caitlin R., Lee, Julie, Goldsmith, Adam M., Jackson, William T., Hoenerhoff, Mark J., Lewis, Toby C., Hershenson, Marc B.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668626/
https://ncbi.nlm.nih.gov/pubmed/31089187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0172-2
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