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Using Recombineering to Generate Point Mutations: Oligonucleotide-based “Hit & Fix” Method

Ability to manipulate the genome or design genes with desired mutation is critical for functional studies. Recombineering has made genetic manipulation of large genomic fragments very feasible and efficient. In the bacteriophage lambda-based recombineering system, three prophage genes, exo, bet, and...

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Bibliografiset tiedot
Julkaisussa:Methods Mol Biol
Päätekijät: Chang, Suhwan, Stauffer, Stacey, Sharan, Shyam K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668621/
https://ncbi.nlm.nih.gov/pubmed/22328429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-564-0_9
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