Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells

Manganese (Mn) is an essential trace element, which also causes neurotoxicity in exposed occupational workers. Mn causes mitochondrial toxicity; however, little is known about transcriptional responses discriminated by physiological and toxicological levels of Mn. Identification of such mechanisms c...

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Udgivet i:Front Genet
Main Authors: Fernandes, Jolyn, Chandler, Joshua D., Lili, Loukia N., Uppal, Karan, Hu, Xin, Hao, Li, Go, Young-Mi, Jones, Dean P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668488/
https://ncbi.nlm.nih.gov/pubmed/31396262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00676
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