Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells

Manganese (Mn) is an essential trace element, which also causes neurotoxicity in exposed occupational workers. Mn causes mitochondrial toxicity; however, little is known about transcriptional responses discriminated by physiological and toxicological levels of Mn. Identification of such mechanisms c...

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Publicat a:Front Genet
Autors principals: Fernandes, Jolyn, Chandler, Joshua D., Lili, Loukia N., Uppal, Karan, Hu, Xin, Hao, Li, Go, Young-Mi, Jones, Dean P.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668488/
https://ncbi.nlm.nih.gov/pubmed/31396262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00676
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