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Putrescine as indicator of manganese neurotoxicity: Dose-response study in human SH-SY5Y cells

Disrupted polyamine metabolism with elevated putrescine is associated with neuronal dysfunction. Manganese (Mn) is an essential nutrient that causes neurotoxicity in excess, but methods to evaluate biochemical responses to high Mn are limited. No information is available on dose-response effects of...

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Detalhes bibliográficos
Publicado no:Food Chem Toxicol
Main Authors: Fernandes, Jolyn, Chandler, Joshua D., Liu, Ken H., Uppal, Karan, Go, Young-Mi, Jones, Dean P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008158/
https://ncbi.nlm.nih.gov/pubmed/29684492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2018.04.042
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