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Putrescine as indicator of manganese neurotoxicity: Dose-response study in human SH-SY5Y cells

Disrupted polyamine metabolism with elevated putrescine is associated with neuronal dysfunction. Manganese (Mn) is an essential nutrient that causes neurotoxicity in excess, but methods to evaluate biochemical responses to high Mn are limited. No information is available on dose-response effects of...

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Bibliographische Detailangaben
Veröffentlicht in:Food Chem Toxicol
Hauptverfasser: Fernandes, Jolyn, Chandler, Joshua D., Liu, Ken H., Uppal, Karan, Go, Young-Mi, Jones, Dean P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008158/
https://ncbi.nlm.nih.gov/pubmed/29684492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2018.04.042
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