Functionalization of Brain Region-specific Spheroids with Isogenic Microglia-like Cells

Current brain spheroids or organoids derived from human induced pluripotent stem cells (hiPSCs) still lack a microglia component, the resident immune cells in the brain. The objective of this study is to engineer brain region-specific organoids from hiPSCs incorporated with isogenic microglia-like c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Song, Liqing, Yuan, Xuegang, Jones, Zachary, Vied, Cynthia, Miao, Yu, Marzano, Mark, Hua, Thien, Sang, Qing-Xiang Amy, Guan, Jingjiao, Ma, Teng, Zhou, Yi, Li, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667451/
https://ncbi.nlm.nih.gov/pubmed/31363137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47444-6
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