Deregulation of TLR4 signaling pathway characterizes Bicuspid Aortic valve syndrome

Bicuspid aortic valve (BAV) disease is recognized to be a syndrome with a complex and multifaceted pathophysiology. Its progression is modulated by diverse evolutionary conserved pathways, such as Notch-1 pathway. Emerging evidence is also highlighting the key role of TLR4 signaling pathway in the a...

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Udgivet i:Sci Rep
Main Authors: Balistreri, Carmela R., Marullo, Antonino G. M., Madonna, Michele, Cavarretta, Elena, Allegra, Alberto, Cesarini, Valeriana, Iaccarino, Alessandra, Schiavon, Sonia, Peruzzi, Mariangela, Greco, Ernesto, Sciarretta, Sebastiano, Pisano, Calogera, Ruvolo, Giovanni, Torella, Michele, Frati, Giacomo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667442/
https://ncbi.nlm.nih.gov/pubmed/31363123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47412-0
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