Deregulation of Notch1 pathway and circulating endothelial progenitor cell (EPC) number in patients with bicuspid aortic valve with and without ascending aorta aneurysm

Bicuspid aortic valve (BAV) is frequently associated with the development of ascending aortic aneurysm, even if the underlying mechanisms remain to be clarified. Here, we investigated if a deregulation of Notch1 signaling pathway and endothelial progenitor cells (EPCs) number is associated with BAV...

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Vydáno v:Sci Rep
Hlavní autoři: Balistreri, Carmela R., Crapanzano, Floriana, Schirone, Leonardo, Allegra, Alberto, Pisano, Calogera, Ruvolo, Giovanni, Forte, Maurizio, Greco, Ernesto, Cavarretta, Elena, Marullo, Antonino G. M., Sciarretta, Sebastiano, Frati, Giacomo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138685/
https://ncbi.nlm.nih.gov/pubmed/30218064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32170-2
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