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PathwayMatcher: proteoform-centric network construction enables fine-granularity multiomics pathway mapping

BACKGROUND: Mapping biomedical data to functional knowledge is an essential task in bioinformatics and can be achieved by querying identifiers (e.g., gene sets) in pathway knowledge bases. However, the isoform and posttranslational modification states of proteins are lost when converting input and p...

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Detalhes bibliográficos
Publicado no:Gigascience
Main Authors: Sánchez, Luis Francisco Hernández, Burger, Bram, Horro, Carlos, Fabregat, Antonio, Johansson, Stefan, Njølstad, Pål Rasmus, Barsnes, Harald, Hermjakob, Henning, Vaudel, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667378/
https://ncbi.nlm.nih.gov/pubmed/31363752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giz088
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