PathwayMatcher: proteoform-centric network construction enables fine-granularity multiomics pathway mapping

BACKGROUND: Mapping biomedical data to functional knowledge is an essential task in bioinformatics and can be achieved by querying identifiers (e.g., gene sets) in pathway knowledge bases. However, the isoform and posttranslational modification states of proteins are lost when converting input and p...

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Publicat a:Gigascience
Autors principals: Sánchez, Luis Francisco Hernández, Burger, Bram, Horro, Carlos, Fabregat, Antonio, Johansson, Stefan, Njølstad, Pål Rasmus, Barsnes, Harald, Hermjakob, Henning, Vaudel, Marc
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Technical Note
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667378/
https://ncbi.nlm.nih.gov/pubmed/31363752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giz088
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