PathwayMatcher: proteoform-centric network construction enables fine-granularity multiomics pathway mapping

BACKGROUND: Mapping biomedical data to functional knowledge is an essential task in bioinformatics and can be achieved by querying identifiers (e.g., gene sets) in pathway knowledge bases. However, the isoform and posttranslational modification states of proteins are lost when converting input and p...

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Vydáno v:Gigascience
Hlavní autoři: Sánchez, Luis Francisco Hernández, Burger, Bram, Horro, Carlos, Fabregat, Antonio, Johansson, Stefan, Njølstad, Pål Rasmus, Barsnes, Harald, Hermjakob, Henning, Vaudel, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Technical Note
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6667378/
https://ncbi.nlm.nih.gov/pubmed/31363752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giz088
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