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Decreased BDNF Levels Are a Major Contributor to the Embryonic Phenotype of Huntingtin Knockdown Zebrafish

Huntington's disease (HD) is an autosomal dominant, neurodegenerative condition caused by a CAG trinucleotide repeat expansion that is translated into an abnormally long polyglutamine tract in the protein huntingtin. Genetic and transgenic studies suggest that the mutation causes disease predom...

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Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Diekmann, Heike, Anichtchik, Oleg, Fleming, Angeleen, Futter, Marie, Goldsmith, Paul, Roach, Alan, Rubinsztein, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666080/
https://ncbi.nlm.nih.gov/pubmed/19193881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6039-08.2009
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