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Wild-type but not mutant huntingtin modulates the transcriptional activity of liver X receptors
BACKGROUND: Huntington’s disease is caused by expansion of a polyglutamine tract found in the amino-terminal of the ubiquitously expressed protein huntingtin. Well studied in its mutant form, huntingtin has a wide variety of normal functions, loss of which may also contribute to disease progression....
Kaydedildi:
| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMJ Publishing Group
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696822/ https://ncbi.nlm.nih.gov/pubmed/19451134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2009.066399 |
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