Astrocytes Modify Migration of PBMCs Induced by β-Amyloid in a Blood-Brain Barrier in vitro Model

BACKGROUND: The brain is protected by the blood-brain barrier (BBB), constituted by endothelial cells supported by pericytes and astrocytes. In Alzheimer’s disease a dysregulation of the BBB occurs since the early phases of the disease leading to an increased access of solutes and immune cells that...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Spampinato, Simona Federica, Merlo, Sara, Fagone, Evelina, Fruciano, Mary, Barbagallo, Cristina, Kanda, Takashi, Sano, Yasuteru, Purrello, Michele, Vancheri, Carlo, Ragusa, Marco, Sortino, Maria Angela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664149/
https://ncbi.nlm.nih.gov/pubmed/31396056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00337
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