Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?

The ability of the Blood Brain Barrier (BBB) to maintain proper barrier functions, keeping an optimal environment for central nervous system (CNS) activity and regulating leukocytes’ access, can be affected in CNS diseases. Endothelial cells and astrocytes are the principal BBB cellular constituents...

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發表在:PLoS One
Main Authors: Spampinato, Simona F., Obermeier, Birgit, Cotleur, Anne, Love, Anna, Takeshita, Yukio, Sano, Yasuteru, Kanda, Takashi, Ransohoff, Richard M.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511229/
https://ncbi.nlm.nih.gov/pubmed/26197437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133392
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