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Chloride to the rescue

On the fiftieth anniversary of the discovery of the Ser-His-Asp catalytic triad, perhaps the most unusual variation on the textbook classic is described: An incomplete catalytic triad in a hydrolase is rescued by a chloride ion (Fig. 1). Structural and functional data provide compelling evidence tha...

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Bibliographic Details
Published in:J Biol Chem
Main Author: Newcomer, Marcia E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6663875/
https://ncbi.nlm.nih.gov/pubmed/31350284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H119.009687
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