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A new regulatory mechanism for Raf kinase activation, retinoic acid-bound Crabp1
The rapidly accelerated fibrosarcoma (Raf) kinase is canonically activated by growth factors that regulate multiple cellular processes. In this kinase cascade Raf activation ultimately results in extracellular regulated kinase 1/2 (Erk1/2) activation, which requires Ras binding to the Ras binding do...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6662813/ https://ncbi.nlm.nih.gov/pubmed/31358819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47354-7 |
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