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Roles of matricellular CCN2 deposited by osteocytes in osteoclastogenesis and osteoblast differentiation

In this study, we investigated the effect of CCN2 (cellular communication network factor 2), previously termed connective tissue growth factor, deposited in bone matrix on osteoclastogenesis and osteoblast differentiation. To mimic the bone matrix environment, osteocytic MLO-Y4 cells had been embedd...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Nishida, Takashi, Kubota, Satoshi, Yokoi, Hideki, Mukoyama, Masashi, Takigawa, Masaharu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662664/
https://ncbi.nlm.nih.gov/pubmed/31358778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47285-3
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