H(+) Transport is an Integral Function of the Mitochondrial ADP/ATP Carrier

The mitochondrial ADP/ATP carrier (AAC) is a major transport protein of the inner mitochondrial membrane. It exchanges mitochondrial ATP for cytosolic ADP and controls cellular ATP production. In addition, AAC may mediate mitochondrial uncoupling, but this AAC function and its mechanisms remain elus...

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Udgivet i:Nature
Main Authors: Bertholet, Ambre M., Chouchani, Edward T., Kazak, Lawrence, Angelin, Alessia, Fedorenko, Andriy, Long, Jonathan Z., Vidoni, Sara, Garrity, Ryan, Cho, Joonseok, Terada, Naohiro, Wallace, Douglas C., Spiegelman, Bruce M., Kirichok, Yuriy
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662629/
https://ncbi.nlm.nih.gov/pubmed/31341297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1400-3
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