Mitochondrial Patch-Clamp of Beige Adipocytes Reveals UCP1-positive and UCP1-negative Cells Both Exhibiting Futile Creatine Cycling

Cold and other environmental factors induce “browning” of white fat depots — development of beige adipocytes with morphological and functional resemblance to brown fat. Similar to brown fat, beige adipocytes are assumed to express mitochondrial uncoupling protein 1 (UCP1) and are thermogenic due to...

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Publicado en:Cell Metab
Autores principales: Bertholet, Ambre M., Kazak, Lawrence, Chouchani, Edward T., Bogaczyńska, Marta G., Paranjpe, Ishan, Wainwright, Gabrielle L., Bétourné, Alexandre, Kajimura, Shingo, Spiegelman, Bruce M., Kirichok, Yuriy
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448977/
https://ncbi.nlm.nih.gov/pubmed/28380374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.03.002
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