The Futile Creatine Cycle powers UCP1-independent thermogenesis in classical BAT
Abstract Classical brown adipose tissue (BAT) is traditionally viewed as relying exclusively on uncoupling protein 1 (UCP1) for thermogenesis via inducible proton leak. However, the physiological significance of UCP1-independent mechanisms linking substrate oxidation to ATP turnover in classical BAT...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2025-04-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-025-58294-4 |
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