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α-Synuclein pathology spread through the brain connectome is modulated by selective vulnerability and predicted by network analysis
Studies of patients afflicted by neurodegenerative diseases suggest that misfolded proteins spread through the brain along anatomically-connected networks, prompting progressive decline. Recently, mouse models have recapitulated the cell-to-cell transmission of pathogenic proteins and neuron death o...
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| Publicado no: | Nat Neurosci |
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| Principais autores: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6662627/ https://ncbi.nlm.nih.gov/pubmed/31346295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-019-0457-5 |
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