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Gene expression models based on transcription factor binding events confer insight into functional cis-regulatory variants
MOTIVATION: Deciphering the functional roles of cis-regulatory variants is a critical challenge in genome analysis and interpretation. It has been hypothesized that altered transcription factor (TF) binding events are a central mechanism by which cis-regulatory variants impact gene expression levels...
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| Опубликовано в: : | Bioinformatics |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6662294/ https://ncbi.nlm.nih.gov/pubmed/30541050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty992 |
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