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Using PARP Inhibitors in Advanced Ovarian Cancer Running head: PARP Inhibitors in Ovarian Cancer

Poly(ADP-ribose) polymerase (PARP) proteins are used by cells in several DNA repair processes. PARP inhibition can result in preferential death of cancer cells when another mechanism for repairing DNR is defective. Two PARP inhibitors, olaparib and rucaparib, have been approved by the US Food and Dr...

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Detalhes bibliográficos
Publicado no:Oncology (Williston Park)
Autor principal: O’Cearbhaill, Roisin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662180/
https://ncbi.nlm.nih.gov/pubmed/30080919
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