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Using PARP Inhibitors in Advanced Ovarian Cancer Running head: PARP Inhibitors in Ovarian Cancer
Poly(ADP-ribose) polymerase (PARP) proteins are used by cells in several DNA repair processes. PARP inhibition can result in preferential death of cancer cells when another mechanism for repairing DNR is defective. Two PARP inhibitors, olaparib and rucaparib, have been approved by the US Food and Dr...
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| Udgivet i: | Oncology (Williston Park) |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6662180/ https://ncbi.nlm.nih.gov/pubmed/30080919 |
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