Distinct structural classes of activating FOXA1 alterations in advanced prostate cancer

Forkhead box A1 (FOXA1) is a pioneer transcription factor that is essential for the normal development of several endoderm-derived organs, including the prostate gland(1,2). FOXA1 is frequently mutated in the hormone-receptor driven prostate, breast, bladder, and salivary gland tumors(3–8). However,...

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Publicado no:Nature
Main Authors: Parolia, Abhijit, Cieslik, Marcin, Chu, Shih-Chun, Xiao, Lanbo, Ouchi, Takahiro, Zhang, Yuping, Wang, Xiaoju, Vats, Pankaj, Cao, Xuhong, Pitchiaya, Sethuramasundaram, Su, Fengyun, Wang, Rui, Feng, Felix Y., Wu, Yi-Mi, Lonigro, Robert J., Robinson, Dan R., Chinnaiyan, Arul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661908/
https://ncbi.nlm.nih.gov/pubmed/31243372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1347-4
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