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Multivalent proteins rapidly and reversibly phase-separate upon osmotic cell volume change
Processing bodies (PB) and stress granules (SG) are prominent examples of sub-cellular, membrane-less compartments that are observed under physiological and stress conditions, respectively. We observe that the trimeric PB protein DCP1A rapidly (within ~10 s) phase-separates in mammalian cells during...
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| Publicado en: | Mol Cell |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7502480/ https://ncbi.nlm.nih.gov/pubmed/32857953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.08.004 |
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